Scientists discovered a special substance in the skin and mucous membranes of animals and humans - defensins. These are natural antibiotics, which makes the body itself. Otkrtie can make a revolution in pharmacology, as an opportunity to make a completely harmless drug.
In the middle of the XIX century, the famous French scientist Louis Pasteur laid the foundations of modern microbiology and immunology, has proven microbial nature of some diseases, developed methods buy prednisone online for preventive vaccination against many serious infections, but not against all. Therefore, doctors dreamed of creating such drugs, which destroy disease-causing viruses and bacteria do not cause harm to the human body.
In 1929, the English microbiologist Alexander Fleming received a penicillin antibiotic, be detrimental to many species of bacteria. In 1940 he was selected purified penicillin, and thanks to him that the doctors have saved hundreds of thousands of human lives. In medicine, the era of antibiotics, continues to this day.
Every year, scientists synthesize new antibiotics, currently there are more than 20 thousand and is not the limit. Today successfully treated severe infectious diseases, traditionally considered incurable, - tuberculosis, cholera, typhoid fever, meningitis, pneumonia. Sometimes it seems that there is a antibiotic and it is time to stop for each disease. But this is not the case. Micro-organisms (viruses, bacteria, fungi) - too insidious "enemy", over millions of years, they have improved their adaptive function.
There is no doubt that most of them when dealing with natural antibiotic die immediately. But some still acquire resistance to it. Since microbes (including survivors) are very fertile, the number of drug-resistant microorganisms growing rapidly. And the antibiotic is no longer helping. Doctors are beginning to develop new natural antibiotic. All repeats. The circle is closed.
The most dangerous is the critical moment when the germs that cause any disease, no longer afraid of old antibiotics and new ones have not yet been created. Therefore, the creators and producers of drugs have to work all the time to be proactive, anticipating the "response" from the microbes, which are becoming more and more "inventive".
It has been fixed resistance to antibiotic agents of dysentery and some slozhnoizlechimyh infections, sexually transmitted diseases. Then they added the ubiquitous pneumococci and streptococci. At first, they ceased to be afraid of his main "enemy" - penicillin, and then quickly adapted to other antibiotics. Caused by these microbes severe infections affecting the eyes, blood formation system, many human organs, began to freely spread across the planet. And to treat them is becoming increasingly difficult - yet is not such a drug that is able to resist bacteria mutants.
In 1997 in Japan, it was discovered a new species of Staphylococcus aureus resistant to all known antibiotics to medical science. Following this, but in North America, there have been reports of experts about the same invincible forms of streptococcus. Consequently, Staphylococcus aureus goes into the category of deadly microorganisms. But it is among the most popular of their kind. In Russia, there were periods when every fifth newborn was infected with the staphylococcus.
Now there is increasing incidence of tuberculosis, and unfortunately, our country is no exception. Cause this disease antibiotic-resistant forms of TB bacilli. Given their tremendous stability in the external environment, doctors predict in the near future, new outbreak of tuberculosis in the world.
However, some experts are more optimistic. In particular, scientists of the Center for adaptation of genetics at Boston University are developing a series of powerful new-generation antibiotics, against which, in their opinion, can not stand most of the mutated bacteria, including Staphylococcus aureus.
Director of the Centre, the famous microbiologist S. Lévi, believes that the spread of antibiotic-resistant bacteria is largely to blame for the people themselves. It's no secret that antibiotics are often not taken serious medical condition, and on the advice of friends and acquaintances, as well as peculiar habit for most people to be treated. In humans, acute rhinitis - he grabs the antibiotics. Easy unwell with fever - and again we ourselves prescribe antibiotics. Living in our bacteria are constantly exposed to the drug attacks, gradually get used to them, mutate, and when it really comes a serious illness, the deal with the "derived" us the same bacteria mutant organism is not easy.
Unfortunately, many doctors in the case and no case like to prescribe antibiotics. In the United States, for example, issued annually over 50 million prescriptions for antibiotics that at least half of the cases is not justified.
Antibiotics - are not harmless drugs. Already in the title of their celebrated their main property - to kill all living things. Prolonged treatment with some antibiotics affects the liver and kidneys, causing severe allergies, destroys intestinal microflora. A powerful surge of fungal disease is also largely provoked by taking antibiotics, it is, in principle, the form of dysbiosis.
The search for new forms of antibiotics, as already mentioned, is continuing. But more and more pharmacists around the world are convinced that it is time to change the strategy of this search. And here, just what we needed, biochemists, specialists found in animals and humans natural antibiotics. This discovery seems to change not only the basics concepts of protective forces of the living organism, but also looks at what antibiotics will be needed in the near future.
Somehow we do not think about why, for example, frog, floundering in the marshes, teeming with a variety of microorganisms, infectious diseases do not get sick and, moreover, the feel of the real dirt quite comfortable. Or why a cow eating grass, completely studded with microbes - are healthy, and if they get sick, then for another reason. Homeless stray dogs, thirsty, drink water from stagnant pools, oversaturated by different types of bacteria. All wild and domestic animals, being surrounded by pathogens, for some reason, has not yet died out. What protects them from infection?